Advanced Health MOT

A comprehensive private blood test for a deeper understanding of your health. Understand your health. Know what to do next. The Swan Science Advanced Annual Health MOT is our most comprehensive annual health assessment in this range, combining extensive blood testing with a urine assessment to explore multiple aspects of your health. Building on our standard Annual Health MOT, the Advanced assessment includes additional markers covering hormonal health, digestive health, pancreatic function, immune activity and nutritional status. Whether you're establishing a health baseline, approaching midlife or monitoring changes over time, this private health check provides a detailed picture of selected biomarkers and a useful starting point for informed conversations about your health. £349, including professional blood collection, laboratory analysis and a detailed results report.

Why choose the Advanced Annual Health MOT?

Comprehensive private health testing Bring together a broad range of laboratory measurements in one assessment, including advanced cardiovascular, metabolic, hormonal and nutritional markers. Extended hormonal assessment Explore selected male or female hormone markers that are not included in the standard Annual Health MOT. Additional digestive and immune markers Includes testing for Helicobacter pylori, antibodies relevant to coeliac disease investigation, immunoglobulins and selected inflammatory markers. More detailed nutritional insights Assess vitamin D, vitamin B12, folate, minerals and total antioxidant status. Establish your baseline Create a reference point for comparing selected health markers over time. Monitor changes when appropriate Arrange repeat testing of individual biomarkers or smaller panels through Swan Science. Repeat tests are purchased separately. Professional blood collection included Your £349 assessment includes professional blood collection, laboratory testing and a detailed results report.

How does the Advanced Annual Health MOT work?

Step 1. Order your private health check Purchase your Advanced Annual Health MOT securely through Swan Science for £349. Step 2. Confirm your assessment We'll contact you by email to confirm which male or female panel is appropriate before arranging your test. Step 3. Arrange sample collection We'll provide instructions for professional venous blood collection at an available collection location. The assessment requires blood and urine samples. Professional blood collection is included in the purchase price. Step 4. Laboratory analysis Your samples are analysed by a specialist pathology laboratory using established laboratory testing methods. Step 5. Receive your results You'll receive a detailed laboratory report showing your measured biomarkers alongside relevant reference ranges. We'll confirm the expected turnaround when arranging your assessment. Collection, transport and laboratory processing can affect the total time required. Results requiring further assessment should be discussed with your GP or another appropriately qualified healthcare professional.

What does the Advanced Annual Health MOT measure?

The Advanced Annual Health MOT covers the following laboratory biomarkers and health markers.

1. Heart and cardiovascular health

An advanced assessment of specialised lipoproteins and markers associated with cardiovascular risk. Biomarkers: Apolipoprotein A-I (ApoA-I), Apolipoprotein B (ApoB), Apolipoprotein B/A-I Ratio, Apolipoprotein CII, Apolipoprotein CIII, Apolipoprotein E, Cardiovascular Risk Score, High-Sensitivity C-Reactive Protein (hsCRP), Lipoprotein(a) [Lp(a)] and Small LDL Cholesterol.

2. Full blood count

Provides information about red blood cells, white blood cells and platelets, which play important roles in oxygen transport, immune function and blood clotting. Biomarkers: Haemoglobin, Haematocrit, Mean Cell Haemoglobin (MCH), Mean Cell Haemoglobin Concentration (MCHC), Mean Cell Volume (MCV), Red Blood Cell Count, Basophil Count, Eosinophil Count, Lymphocyte Count, Monocyte Count, Neutrophil Count, White Blood Cell Count and Platelet Count.

3. Iron status

Measures circulating iron, iron stores and iron transport, helping identify patterns associated with low or elevated iron levels. Biomarkers: Iron, Ferritin, Total Iron Binding Capacity (TIBC), Transferrin and Transferrin Saturation.

4. Diabetes and blood sugar health

Assesses markers associated with blood glucose regulation, insulin production and longer-term blood sugar levels. Biomarkers: Glucose, HbA1c (Glycated Haemoglobin), Insulin and C-Peptide.

5. Metabolic health

Measures selected hormones associated with appetite regulation, energy balance and metabolic processes. Biomarkers: Leptin, Adiponectin and Resistin. These provide additional metabolic information and are not standalone diagnostic tests for metabolic disorders.

6. Liver health

Measures liver-related enzymes and proteins that can provide information about liver health and possible abnormalities. Biomarkers: Alkaline Phosphatase (ALP), Alanine Aminotransferase (ALT), Aspartate Aminotransferase (AST), Gamma-Glutamyltransferase (GGT), Total Bilirubin and Albumin.

7. Kidney health

Assesses markers relating to kidney filtration, waste removal and electrolyte balance. Biomarkers: Creatinine, Estimated Glomerular Filtration Rate (eGFR), Chloride, Potassium, Phosphate, Sodium, Urea, Cystatin C, Magnesium and Uric Acid.

8. Thyroid health

A detailed thyroid assessment including hormones and antibodies relevant to thyroid function and possible autoimmune thyroid activity. Biomarkers: Thyroid Stimulating Hormone (TSH), Free Tri-iodothyronine (FT3), Free Thyroxine (FT4), Anti-Thyroglobulin Antibody (Anti-Tg) and Anti-Thyroid Peroxidase Antibody (Anti-TPO).

9. Nutritional health

An extended assessment of selected vitamins, minerals and nutritional markers. Biomarkers: Adjusted Calcium, Albumin, Iron, Vitamin D, Magnesium, Folic Acid (Folate), Vitamin B12 and Total Antioxidant Status (TAS).

10. Bone health

Measures selected biochemical markers associated with bone metabolism and mineral balance. Biomarkers: Alkaline Phosphatase (ALP), Adjusted Calcium, Phosphate and Vitamin D.

11. Inflammation and immune health

The Advanced assessment includes additional proteins and immune markers that can provide information about aspects of inflammatory and immune activity. Biomarkers:

• C-Reactive Protein (CRP)
• Albumin
• Complement Component 3 (C3)
• Complement Component 4 (C4)
• Ferritin
• Immunoglobulin A (IgA)
• Immunoglobulin G (IgG)
• Immunoglobulin M (IgM)
• Anti-Streptolysin O (ASO)

These markers are not sufficient to diagnose or exclude immune disorders or infections independently.

12. Digestive health

Includes selected tests that may contribute to investigations of gastrointestinal conditions. Markers:

• Helicobacter pylori (H. pylori)
• Anti-Tissue Transglutaminase Antibodies

These results require appropriate clinical interpretation. The tests do not independently confirm or exclude all digestive conditions. In particular, H. pylori results must be interpreted according to the testing method, while coeliac antibody results may require further clinical assessment.

13. Pancreatic health

Measures enzymes associated with pancreatic function and potential pancreatic abnormalities. Biomarkers:

• Pancreatic Amylase
• Lipase

14. Allergy evaluation

Includes a general marker associated with allergic and other immune responses. Biomarker:

• Total Immunoglobulin E (Total IgE)

Total IgE does not identify specific allergens and cannot diagnose or rule out an allergy on its own.

15. Muscle and joint health

Includes a biochemical marker associated with purine metabolism and conditions such as gout. Biomarker:

• Uric Acid

16. Urinary health

A urine assessment providing information about selected urinary tract and metabolic markers. Markers: Bilirubin, Glucose, Ketones, Nitrite, pH, Protein, Red Blood Cells, Urobilinogen and White Blood Cells.

17. Male and female hormonal health

The Advanced Annual Health MOT includes additional hormone testing, with different markers according to the selected panel. Female hormonal health

• Oestradiol
• Follicle Stimulating Hormone (FSH)
• Luteinising Hormone (LH)
• Progesterone
• Prolactin
• Testosterone
• Sex Hormone Binding Globulin (SHBG)
• Free Androgen Index (FAI)

Hormone levels can vary with age, menstrual cycle stage, medication and other factors. Results require appropriate clinical interpretation. Male hormonal health

• Testosterone
• Sex Hormone Binding Globulin (SHBG)
• Free Androgen Index (FAI)

These markers provide information relevant to androgen status. They do not independently diagnose hormonal disorders.

18. Male and female tumour markers

The assessment also includes a different marker according to the selected panel. Male Advanced Annual Health MOT Includes Total Prostate Specific Antigen (TPSA), a marker used in the clinical assessment of prostate health. Female Advanced Annual Health MOT Includes Cancer Antigen 125 (CA-125), a marker used in certain clinical investigations and monitoring of gynaecological conditions. Important: Neither PSA nor CA-125 can reliably diagnose or exclude cancer on its own. CA-125 is not recommended as a routine ovarian cancer screening test for people without symptoms. If you have symptoms or concerns about cancer, please consult your GP for appropriate clinical assessment rather than relying on this test. Swan Science will contact you after purchase to confirm the appropriate male or female panel. Some biomarkers appear in more than one health category because they are relevant to several areas. They are not measured multiple times.

How does the Advanced MOT compare with the standard Annual Health MOT?

Both assessments provide a comprehensive private blood test and health check, including advanced cardiovascular markers, blood and iron status, diabetes and metabolism, liver and kidney function, thyroid health, nutritional markers and urinalysis. The Advanced Annual Health MOT (£349) adds further testing covering:

• Male or female hormonal health
• Digestive health, including H. pylori and antibodies relevant to coeliac disease
• Pancreatic enzymes
• Additional inflammatory and immune markers
• Total IgE
• Vitamin B12 and folate
• Total antioxidant status

The standard Annual Health MOT (£249) remains an extensive option for establishing a general health baseline. More testing is not necessarily better for every person. If you're unsure which assessment is suitable, contact Swan Science before purchasing.

Who is the Advanced Annual Health MOT for?

The Advanced Annual Health MOT is designed for adults interested in a broader laboratory assessment of selected health markers. It may be suitable if you:

• Want a wider assessment than the standard Annual Health MOT.
• Are particularly interested in hormonal or metabolic markers.
• Want to establish a detailed baseline for future comparisons.
• Have made lifestyle changes and want to monitor selected measurements.
• Are interested in the additional digestive, immune or nutritional markers.
• Prefer an extensive predefined private health check rather than purchasing several separate tests.

The inclusion of a particular marker does not mean it is clinically indicated for every customer. If you have symptoms, a medical condition or concerns requiring investigation, a healthcare professional can advise which tests are appropriate.

Understand your results. Track your health over time.

Your results provide a snapshot of selected biomarkers at the time of testing. They can help establish a personal health baseline and identify measurements that may be useful to compare following changes in lifestyle, medication or health. You don't necessarily need to repeat the entire Advanced Annual Health MOT to monitor selected markers. Individual biomarkers and smaller testing panels may be available through Swan Science, allowing you to arrange further testing where appropriate. Repeat tests are purchased separately, and the appropriate interval depends on the markers being measured and your circumstances. Understand your health. Know what to do next.

Important information

The Advanced Annual Health MOT provides laboratory information about selected biomarkers. It does not diagnose or exclude every medical condition, replace professional medical advice or replace NHS screening programmes. Some included markers, particularly PSA, CA-125, total IgE, H. pylori and coeliac antibodies, have specific limitations and must be interpreted in the appropriate clinical context. Laboratory test availability, sample requirements and biomarker menus may occasionally change. If a particular biomarker is important to you, please contact Swan Science before purchasing. Results should be interpreted in the context of your symptoms, medical history, medication and other relevant factors. If you have symptoms, abnormal results or concerns about your health, consult an appropriate healthcare professional. The expected results timeframe is an estimate rather than a guarantee.